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Helps calm nerves and promotes healthy sleep
Chronic daily stress is detrimental to both mental and physical health, impacting sleep and exhausting the body’s stress-coping mechanisms. Ashwagandha (Withania somnifera) is a plant in the nightshade family that has been used traditionally in Ayurvedic medicine to improve the body’s resistance to mental and physical stress. (1) Its main active phytochemicals are a group of steroidal alkaloids and lactones known as withanolides. (2)
As an adaptogen, ashwagandha has an important role in natural stress relief and has been shown to improve self-reported and physiological markers commonly associated with stress. (2) In a placebo-controlled study, healthy adults suffering from mild stress took a single 240 mg dose of ashwagandha extract per day. After 60 days of supplementation, participants were found to have a 41% reduction in ratings of nervousness and a 30% (near-significant) reduction on scales of unhappiness, nervousness, and stress. Participants were also shown to have lower levels of the stress hormone cortisol, compared to the placebo. (2)
Sleep helps rejuvenate the body both physically and biochemically. Ashwagandha is a recognized Rasayana (rejuvenation tonic) in Ayurvedic medicine with the ability to aid sleep. This may be related to its cortisol-lowering effects, which is important for maintaining a normal circadian rhythm. (3) A placebo-controlled trial examined the effects of daily 125 mg, 250 mg, and 500 mg doses of ashwagandha extract on stressed patients for 60 days. All doses were shown to significantly improve Hamilton anxiety scale measures of stress, including symptoms of fatigue and sleeplessness. Biochemical measures of stress, including blood levels of cortisol, fasting glucose, lipids, markers of oxidative stress, and the androgen dehydroepiandrosterone, were shown to improve in a dose-dependent manner. (3)
Rhodiola (Rhodiola rosea) is traditionally used in herbal medicine to temporarily relieve symptoms of stress, such as mental fatigue and feelings of weakness. (4) It is one of the best-known adaptogens available, with studies supporting its ability to strengthen the body against chemical, biological, and physical stressors. Because chronic stress interferes with memory and mental well-being, rhodiola can be used to enhance cognitive function, such as mental focus and stamina. It also provides antioxidants. (5)
Valerian (Valeriana officinalis) is traditionally used in herbal medicine to help relieve nervousness (calmative) and promote sleep. It is the most common herbal remedy used in the United States and Europe for inducing sleep. (6) Its mild sleep-inducing effects are considered non-habit forming and do not have a negative impact on sleep structure. A systematic review of valerian studies on doses ranging between 90–600 mg per day found that patients taking valerian had an 80% greater rate of improved sleep quality than placebo groups. (7)
Quercetin, an antioxidant bioflavonoid found in fruits and vegetables, has been shown to improve the body’s antioxidant status. (7) Animal studies also support its therapeutic potential for conditions related to stress. Piperine is the main active component of black pepper and is recognized for enhancing the bioavailability of quercetin. (8)
Each capsule contains:
Ashwagandha Extract (Withania somnifera) (root) (3% withanolides).............. 187.5 mgValerian Extract 3:1 (Valeriana officinalis) (root) (0.8% valerenic acid).............. 150 mgLyophilized Adrenal Tissue (cattle) (Bos taurus) (adrenal gland).............. 37.5 mgQuercetin (Styphnolobium japonicum) (flower bud)............... 25 mgRhodiola Extract (Rhodiola rosea) (root) (3.5% rosavins)............... 12.5 mgBioPerine® Black Pepper Extract (Piper nigrum) (fruit) (standardization 95% piperine)............... 625 mcg
Non-medicinal Ingredients: Rice starch, gelatin capsule (gelatin, purified water), citrus bioflavonoids, vegetable grade magnesium stearate (lubricant).
This product does not contain artificial preservatives, colours, or sweeteners; no dairy, sugar, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, salt, tree nuts, or GMOs.
Recommended adult dose: 1 capsule 2 times daily with food or as directed by a health care practitioner. For use beyond 12 weeks, consult a health care practitioner.
Caution: For adult use only. Piperine may increase the bioavailability of drugs and natural health products. Avoid taking with alcohol or products with sedative properties or products that increase drowsiness. Consult a health care practitioner prior to use if you are pregnant or breastfeeding, are taking prescription medications or have a serious medical condition, if you have asthma or are taking asthma medication or corticosteroids. Some people may experience drowsiness. Exercise caution if operating heavy machinery, driving a motor vehicle, or involved in activities requiring mental alertness. Consult a health care practitioner if symptoms persist or worsen, or if sleeplessness persists continuously for more than 4 weeks (chronic insomnia). Keep out of reach of children.
What exactly is "Lyophilized Adrenal Tissue"?
We use whole adrenal tissue sourced from bovine; the part of the adrenal gland used is the cortex and the medulla. "Lyophilized" means that this is a very absorbable form of adrenal tissue. The lyophilizing process preserves the natural makeup of the original gland, making it highly potent yet well tolerated. In addition, this form of processing also allows for superior bio-availability.
What is the source used for the ingredient "citrus bioflavonoid" in Brad King's Ultimate Anti-Stress?
The source used for the citrus bioflavonoids powder is from the peel and rind of the fruit itself. As a citrus powder product, the type of citrus used is seasonally dependent, but is typically from lemon and grapefruit.
Your label shows that Anti-Stress lowers cortisol. What if it doesn't need to be lowered, but my adrenals are weak?The ingredients in this formula have been shown to help support weak adrenals. In some cases if cortisol is too high (as it is with numerous stressful situations) the ingredients will help to lower the cortisol by working to aid in stress adaptation. Ultimate Anti-Stress will help support weak adrenals but will not lower cortisol when it is not necessary.
What makes Anti-Stress better than other adrenal (stress) formulas on the market?
Lyophilized adrenal tissue is a powerful glandular (and part of non-vegan Ultimate Anti-Stress) that possesses synergistic natural compounds that help to replenish and restore healthy adrenal function. Lyophilized adrenal tissue (along with the other natural ingredients in Anti-Stress) has been shown to help support physical or emotional stress, poor stress tolerance, general fatigue, allergies, mood disorders, and many other stress-related concerns.
What is the difference between Anti-Stress and Vegan Anti-Stress (besides the ingredients)?
The Vegan formula of Anti-Stress was introduced as an alternative to the original formula, as this formula contains actual adrenal tissue - resulting in a product that is not suitable for vegetarians and vegans. By removing the adrenal tissue and adding the lemon balm extract instead, we now have a product for everyone, regardless of their diet choices. Both formulas are fine to take ongoing, however the vegan formula might be better suited to individuals who are taking the product for sleep issues and the original formula might be better suited to individuals who are planning to take the product for anxiety issues.
Is Ultimate Anti-Stress gluten free?
Yes, we do have confirmation on file that there is no gluten added and no gluten present in the Ultimate Anti-Stress formula. However, our manufacturing facility is NOT a gluten free facility, and as we do process products that contain gluten we are unable to confirm 100% that there is no possibility of cross contamination.
Are Brad King's products WADA certified?
No, we do not have an official WADA (World Anti-Doping Agency) designation or release on our Ultimate products by Brad King.
I have noticed that many of Brad King's products contain an ingredient called "Bioperine Black Pepper Extract". What exactly is this?
This black pepper is not the same as pure black pepper. It is actually a standardized extract from the fruit of black pepper (containing 95% piperine). It is used in the majority of the Ultimate products to increase the bio-availability of the nutrients within these formulas. Bioperine is the only source from piperine to have undergone clinical studies in the U.S. to substantiate its complete safety and research-proven efficacy for nutritional use. Many individuals have difficulty absorbing and utilizing nutrients within nutritional formulas. The Ultimate products insure that people are not only getting the best formulas possible, but that they are actually absorbing and utilizing what they are paying for.
Do all of your products have an NPN?
Yes, all of our products have been issued a Natural Product Number (NPN) by Health Canada – these numbers do appear on our labels. Further Natural Health Product criteria and information can be found on the Health Canada website www.hc-sc.gc.ca Under the Food and Drugs Act items that are considered a food – for example, our protein powders and herbal teas – do not require an NPN. Are your capsules GMO free?
Yes, our vegetarian capsule shells, our gelatin capsule shells and our softgel shells are all non-GMO.Are your products GMO free?
Preferred Nutrition is currently in the process of testing all of our products so that we can advise the public if any of them contain ingredients that come from genetically modified organisms or not. Once the testing is complete we will indicate on our website, as well as on our product information sheets and on our labels. This will be done as quickly as possible and on a product-by-product basis.Why have your cautions and your recommended/suggested usages changed so dramatically on many of your labels?
The changes you are noticing to our suggested usage and cautionary statements have been at the directive of Health Canada. There have been many regulatory changes with regards to Natural Health Products causing companies to change their labels accordingly. We update our website, product information sheets and labels on the actual products to reflect these regulations as quickly as we possibly can. Health Canada and the industry representing natural health products act according to the interest of consumers and their safety. As a result, if there is any concern with an existing condition, a caution is added to advise the consumer to seek out feedback from their Health Care professional. Will this product help me lose weight?
There is no such thing as a "magic" pill or product - the only way to succeed (and maintain) true weight loss is by adopting a healthy lifestyle combining adequate exercise and proper nutrition. If you are concerned about poor eating habits or cravings, then we recommend you seek advice from a Nutritionist or Naturopath to obtain some guidance on healthy eating, as well as to investigate possible underlying (or undiagnosed) hormonal imbalances, which can make it harder to lose weight. You might also want to consider speaking with a personal trainer to help you discover a fun fitness program that you enjoy - because, no matter what, in order to achieve and maintain any type of weight loss, exercise is required. Our vitamins and supplements are designed to help you in your quest to a daily, healthy lifestyle, however it also requires effort on your part.Where do you source your products from?
Please be advised that all of our ingredients, including flavourings, are derived from natural ingredients and are ISURA tested & certified (in order to ensure the absence of GMOs, contaminants, heavy metals and adulteration). All of our products are manufactured at a GMP facility certified by Health Canada. All raw materials come in and are tested for purity, safety and potency. If they do not meet our standards they are rejected and sent back or destroyed. We use the highest quality ingredients available, and choose organic whenever we can. Many of our products contain proprietary patented ingredients that have been clinically researched to help deliver optimal results and outstanding quality.Are your products gluten free?
Unless otherwise indicated, all of our products are manufactured in a facility that is not dedicated to be gluten free. Therefore we cannot guarantee that any of our products are gluten free since there is always a possibility of cross-contamination. Are your products peanut free?
Following compliance with food regulations, in order to make a negative claim such as "peanut free", it would be necessary to insure a zero tolerance of any peanut traces, including the possibility of cross contamination. Although our manufacturing facility has a policy in place for allergen control, there is no specific policy for peanuts, nor is there a specific "no peanut agreement" with our raw material suppliers.Can your products be used after the expiry date has passed?
Supplements generally keep their potency long after the expiry date. There is certainly no safety issues with consuming after the expiry date has passed however the potency degrades over longer periods of time.If a product does not specify "vegetarian capsule", then what is it made from?
These capsules are gelatin capsules sourced from either pork or beef.Are any of your products "vegan-friendly"?
Yes, AdrenaSense, EstroSense, MenoSense, BioSil, Medi-C Plus, Magnesium and MagSense (from our WomenSense and Preferred Nutrition product lines), the Healing Teas, our Ultimate Maca Energy products and the Ultimate VEGAN line are all vegan friendly.
Why can't I find any prices on your website?
Preferred Nutrition is the wholesale distribution company for the products on this website. However we sell exclusively to Health Food stores & selected Natural Pharmacies across Canada, not directly to the general public. Because the prices of our products can vary from store-to-store, we are unable to list our suggested prices on our website. We recommend you contact your local retailer and inquire about prices directly with them. Can I purchase products directly from you? I went to a health food store and the prices seem very expensive.
We distribute our products in Canada only and we sell directly to Health Food stores - since they have a personal commitment to the natural health lifestyle. Consumers are then able to buy our products from knowledgeable staff that are genuinely interested in helping people be well - people who care! Always be sure to look for in store promotions or coupons when you are making your purchases as this can help alleviate your cost concerns.Do all health food stores carry all of your products?
To find Health Food stores in your area that carry our products, please click on "Store Locator" at the top of this screen. All you have to do is enter your postal code and you will be given a list of retailers in the radius that you choose. We do recommend calling ahead to see if they stock the item you are looking for and in most cases if a store does not normally carry something, they will offer to do a special order for you.Are any of your products tested on animals?
No, there is no animal testing on any of our products.Should your supplements be taken with or without food?
Most of our products will specify directly on the bottle whether they should be taken with a meal or not. If nothing is stated, then the choice is yours as to when the best time is for you to take them. In general, however, most vitamin supplements should be taken with food because once eating starts the digestive process, enzymes and gastric juices are generated and usually the nutrients will be absorbed and assimilated better.I like the sound of many of your products. Am I able to take different formulas at the same time?
Yes, it's safe to combine various WomenSense products to help support the body in achieving optimal health. The same applies to the Preferred Nutrition line, Dr. Whitaker's formulas and Brad King's. If you are unsure of any combination, then please consult your Health Care Practitioner.I have heard that drinking green tea along with my supplements will end up flushing out all the nutrients? Is this true?
No, you are fine taking your supplements with green tea. Coffee inhibits the absorption of nutrients, but the caffeine in green tea will not pose the same problem.Can you tell me if I can combine any of your supplements with the medication(s) I am on, as prescribed by my doctor?
It is best to consult your Doctor or alternative Health Practitioner before taking any new supplements while on prescribed medication. If you have been approved to add our supplement(s) to your daily regime, then we do recommend that you space the medication and the supplements out by at least one hour.Can I take your products when I am pregnant or breastfeeding?
We are not able to make any recommendations with any of our products when it comes to pregnancy or while nursing. You must contact your Health Practitioner, Naturopath or Pharmacist.I understand that you put a recommended dosage on your labels, but I can take more or less than that, right? And, really, do I have to take the product every day?
With regards to the recommended dosage, we would suggest you speak to your Doctor or Health Care Practitioner before increasing any amounts. As with any supplement you can determine your amount based on your personal preference - if you find that a product works for you immediately then you should be fine to take it just on the days you feel you need it, but again we suggest you discuss this with you MD or HP. Some consumers find that a product needs to be in their system for a few days to a few weeks before they notice results and/or feel the full benefits. I don't understand why when I purchase your product and open the bottle, the contents don't even fill 1/2 of the packaging that is being used?
The containers we use are determined based on product fill and required label information, as well as capsule count when/where applicable. Sometimes we do have to use a larger bottle than seems necessary because of the information required on the labels - requirements both from Health Canada and in order for the label to be clear and legible to our consumers. Also, in a case where we are offering larger volume (ie/ 400g versus 200g or 180 capsules versus 90 capsules), then we have to put the contents in a bigger container in order for there to be differentiation on the shelf.I bought a bottle of your product, and although it seemed to feel lighter than usual, I didn't think much of it, until I opened the bottle and discovered that there is nowhere near the amount of capsules inside as there should have been. How can this happen?
As part of our corporate policy and Good Manufacturing Practices (GMP) requirement, our procedures incorporate routine in-process checks plus a final examination of the finished product to ensure conformance to all aspects of quality, including correct product count. There are a number of checks and balances performed by both Production and Quality Assurance personnel prior to, during, and after the packaging operations to ensure that product under-counts do not happen. Although product under-counts can happen, this occurrence is rare. Should you discover that your bottle is far below the label claim count upon opening - we recommend you return it to your point of purchase as per our 100% customer satisfaction guarantee.What is your 100% money-back (customer satisfaction) guarantee?
Our 100% money-back/customer satisfaction guarantee ensures that if a customer is not completely satisfied with their purchase, they can return the unused portion of the product (in its original packaging) back to their point of purchase and we will credit the Health Food store 100% of their purchase price from us. We cannot dictate if a store will give cash back or an in-store credit, nor can we override store policies already in place ~ but we do promise to credit them, regardless of the reason for the return.
1. Langade, D., Kanchi, S., Salve, J., et al. (2019). Efficacy and safety of ashwagandha (Withania somnifera) root extract in insomnia and anxiety: A double-blind, randomized, placebo-controlled study. Cureus, 11(9), e5797.
2. Lopresti, A.L., Smith, S.J., Malvi, H., et al. (2019). An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract. A randomized, double-blind, placebo-controlled study. Medicine (Baltimore), 98(37), e17186.
3. Auddy, B., Hazra, J., Mitra, A., et al. (2008). A standardized Withania Somnifera extract significantly reduces stress-related parameters in chronically stressed humans: A double blind, randomized, placebo-controlled study. JANA, 11(1), 50-56.
4. Health Canada. (2019). Single Ingredient Monograph: Rhodiola – Rhodiola rosea. Retrieved from http://webprod.hc-sc.gc.ca/nhpid-bdipsn/atReq.do?atid=rhodiol&lang=eng
5. Khanum, F., Bawa, A.S., & Singh, B. (2005). Rhodiola rosea: A versatile adaptogen. Comprehensive Reviews in Food Science and Food Safety, 4(3), 55-62.
6. Bent, S., Padula, A., Moore, D., et al. (2006). Valerian for sleep: A systematic review and meta-analysis. American Journal of Medicine, 119(12), 1005-1012.
7. Egert, S., Wolffram, S., Bosy-Westphal, A., et al. (2008). Daily quercetin supplementation dose-dependently increases plasma quercetin concentrations in healthy humans. Journal of Nutrition, 138(9), 1615-1621.
8. Singh, S., Jamwal, S., & Kumar, P. (2017). Neuroprotective potential of Quercetin in combination with piperine against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity. Neural Regeneration Research, 12(7), 1137-1144.
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