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Preferred Nutrition®

Berberine 500mg Vegetarian Capsules

Berberine 500mg Vegetarian Capsules


Berberine from Preferred Nutrition is a concentrated barberry root extract used to support healthy glucose metabolism and cardiovascular health in adults. Berberine is an alkaloid that occurs naturally in certain medicinal plants. It is a fantastic option for people who want to support blood sugar balance and healthy cholesterol levels with the convenience of just two vegetarian capsules per day.

  • Supports healthy glucose metabolism
  • Helps maintain cardiovascular health in adults
  • Helps support healthy cholesterol levels
  • Helps support healthy blood lipid levels
  • Supports insulin sensitivity

SKU: PN0423

NPN: 80051589

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Berberine 500mg Vegetarian Capsules

Additional Information

Recommended Dosage

Recommended adult dose: 1 capsule 2 times daily with meals or as directed by a health care practitioner. Consult a health care practitioner for use beyond 3 months.

Allergy Information

This product does not contain artificial preservatives, colours, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs. Suitable for vegetarians/vegans.


Each Vegetarian Capsule Contains:
Medicinal Ingredient:
Berberine (hydrochloride) (Berberis vulgaris) (root bark) 500 mg

Vegetarian capsule (carbohydrate gum, purified water), microcrystalline cellulose, vegetable grade magnesium stearate (lubricant), silica, stearic acid.


Consult a health care practitioner if you have leucopenia, a kidney disorder, hypotension or blood pressure problems. Consult a health care practitioner prior to use if you have hypoglycemia or diabetes. Do not use if you are pregnant or breastfeeding. May cause gastrointestinal discomfort such as constipation, vomiting, abdominal pain or diarrhea, in which case discontinue use and consult a health care practitioner. Keep out of reach of children.


1.       Tabeshpour, J., Imenshahidi, M., & Hosseinzadeh, H. (2017). A review of the effects of Berberis vulgaris and its major component, berberine, in metabolic syndrome. Iran J Basic Med Sci, 20(5), 557-68. Retrieved from

2.       Firouzi, S., Malekahmadi, M., Ghayour-Mobarhan, M., et al. (2018). Barberry in the treatment of obesity and metabolic syndrome: possible mechanisms of action. Diabetes Metab Syndr Obes: Targets and Therapy, 11, 699-705.

3.       Liang, Y., Xu, X., Yin, M., et al. (2019). Effects of berberine on blood glucose in patients with type 2 diabetes mellitus: a systematic literature review and a meta-analysis. Endocr. J, 66(1), 51-63.

4.       Yan, H. M., Xia, M. F., Wang, Y., et al. (2015). Efficacy of berberine in patients with non-alcoholic fatty liver disease. PloS one, 10(8), e0134172.

5.       Yang, J., Yin, J., Gao, H. et al. (2012). Berberine improves insulin sensitivity by inhibiting fat stores and adjusting adipokines profile in human preadipocyte and metabolic syndrome patients. Evid Based Complement Alternat Med, 2012, 363845.

6.       Koppen, L. M., Whitaker, A., Rosene, A., et al. (2017). Efficacy of berberine alone and in combination for the treatment of hyperlipidemia: A systematic review. J Evid Based Complement Alternat Med, 22(4), 956-68.

7.       Zhang, Y., Li, X., Zou, D., et al. (2008). Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine. J Clin Endocrinol, 93(7), 2559-65. Retrieved from

8.       Derosa, G., D’Angelo, A., Bonaventura, A., et al. (2013). Effects of berberine on lipid profile in subjects with low cardiovascular risk. Expert Opin Biol Ther, 13, 475-82.